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Article

Bi-directional effects between inflammatory molecules and intracranial aneurysm.

Neurosurgical review - 21 Nov 2024

Liu Junyu, Yuan Binfeng, Wang Yuge, Yan Junxia

Abstract excerpt

INTRODUCTION: Although inflammation is closely associated with the pathogenesis of intracranial aneurysm (IA), detailed causal associations remain unclear. This study aimed to investigate the causality between circulating inflammatory molecules (IMs) and IA. MATERIALS AND METHODS: The bi-directional Mendelian randomization (MR) analysis was conducted using two genome-wide association studies (GWAS) for...

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PMID: 39570436
DOI: 10.1007/s10143-024-03070-z

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