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Article

Gene Polymorphisms Increasing the Risk of Intracranial Aneurysms: Interleukin-6 -174G>C and -572G>C (Part II).

Acta bio-medica : Atenei Parmensis - 21 Mar 2022

Giotta Lucifero Alice, Baldoncini Matias, Brambilla Ilaria, Rutigliano Monica, Savioli Gabriele, Galzio Renato, Campero Alvaro, Lawton Michael T, Luzzi Sabino

Abstract excerpt

Introduction The interleukin-6 (IL-6), a proinflammatory cytokine, supports the adaptive immune response and regulates inflammatory processes. The -174 G>C and -572 G>C promoter polymorphisms of the IL-6 gene take part in the pathogenesis of intracranial aneurysms (IAs) and influence the clinical presentation of subarachnoid hemorrhage. This meta-analysis purposes to evaluate whether and which IL-6 allelic...

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Identifiers

PMID: 35441611
DOI: 10.23750/abm.v92iS4.12669
PMCID: PMC9179066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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