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The interleukin-6 gene -572G>C promoter polymorphism is related to intracranial aneurysms in Chinese Han nationality.

Neuroscience letters - 25 Jul 2008

Sun Hui, Zhang Dong, Zhao Jizong

Abstract excerpt

There is evidence suggesting that inflammation plays an important role in the pathogenesis of intracranial aneurysms (IAs). Interleukin-6 (IL-6) is an important pro-inflammatory cytokine, and some authors have demonstrated that IL-6 promoter polymorphism -572G>C is associated with IAs in Caucasian population. We performed a case-control study to investigate whether this single nucleotide polymorphism (SNP) might...

Topics

Adolescent
Adult
Aged
Asian People
Case-Control Studies
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Interleukin-6
Intracranial Aneurysm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Polymorphism, Genetic

Promoter Regions, Genetic

Source

Identifiers

PMID: 18487018
DOI: 10.1016/j.neulet.2008.04.077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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