Gene Polymorphisms Increasing the Risk of Intracranial Aneurysms: Interleukin-1β -511C>T (Part I).

doi:10.23750/abm.v92iS4.12668

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Article

Gene Polymorphisms Increasing the Risk of Intracranial Aneurysms: Interleukin-1β -511C>T (Part I).

Acta bio-medica : Atenei Parmensis - 21 Mar 2022

Giotta Lucifero Alice, Baldoncini Matias, Foiadelli Thomas, Brambilla Ilaria, Savioli Gabriele, Galzio Renato, Campero Alvaro, Lawton Michael T, Luzzi Sabino

Abstract excerpt

Introduction Intracranial aneurysms (IAs) are devastating cerebrovascular diseases with multifactorial etiology. The role of inflammation is indisputable, and interleukins are pivotal in supporting local inflammatory pathways and endothelial dysfunction at the aneurysm wall. In the light of insufficient evidence reported in the literature, this meta-analysis was aimed to investigate the genetic linkage between...

Topics

Case-Control Studies
Genetic Predisposition to Disease
Humans
Interleukin-1beta
Intracranial Aneurysm
Polymorphism, Single Nucleotide

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Identifiers

PMID: 35441612
DOI: 10.23750/abm.v92iS4.12668
PMCID: PMC9179052

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