Article
Interactions of interleukin-12A and interleukin-12B polymorphisms on the risk of intracranial aneurysm.
Molecular biology reports - 1 Dec 2012
Li Li-Juan, Pan Xin-Min, Sima Xiutian, Li Zhao-Hui, Zhang Lu-Shun, Sun Hong, Zhu Yi, Liang Wei-Bo, Gao Lin-Bo, Zhang Lin
Abstract excerpt
Several lines of evidence indicate that inflammatory processes play pivotal role in the development of intracranial aneurysm (IA). Recently, polymorphisms in the interleukin-12 (IL-12) gene were shown to be associated with immune-mediated inflammatory disease. The aim of this study was to investigate the interactions of IL-12A and IL-12B polymorphisms on the risk of IA in a Chinese population. A total of 422...
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