Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disrupted topological organization of resting-state functional brain networks in Parkinson's disease patients with glucocerebrosidase gene mutations.

Neuroradiology - 1 Feb 2023

Hou Yanbing, Feng Fei, Zhang Lingyu, Ou Ruwei, Lin Junyu, Gong Qiyong, Shang Huifang

Abstract excerpt

PURPOSE: The mutations of the glucocerebrosidase (GBA) gene are the greatest genetic risk factor for Parkinson's disease (PD). The mechanism underlying the association between GBA mutations and PD has not been fully elucidated. METHODS: Using resting-state functional magnetic resonance imaging and graph theory analysis to investigate the disrupted topological organization in PD patients with GBA mutation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Glucosylceramidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Magnetic Resonance Imaging

Share to Mutation

Share to Parkinson Disease

Share to Pilot Projects

Source

Identifiers

PMID: 36269334
DOI: 10.1007/s00234-022-03067-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disrupted topological organization of resting-state functional brain networks in Parkinson's disease patients with glucocerebrosidase gene mutations.PMID 36269334Read ↗

Altered structural-functional coupling in Parkinson’s diseaseSemantic proximity Read ↗

LRRK2 and GBA Variants Exert Distinct Influences on Parkinson's Disease-Specific Metabolic Networks.Semantic proximity Read ↗

Brain networks and cognitive impairment in Parkinson’s diseaseSemantic proximity Read ↗

Altered Brain Functional Network in Subtypes of Parkinson's Disease: A Dynamic PerspectiveSemantic proximity Read ↗

<i>BIN3</i>rs2280104 T allele is associated with excessive daytime sleepiness and altered network topology in Parkinson’s diseaseSemantic proximity Read ↗

<i>BCKDK</i>rs14235 A allele is associated with milder motor impairment and altered network topology in Parkinson’s diseaseSemantic proximity Read ↗

Parkinson’s disease-associated genetic variants synergistically shape brain networksSemantic proximity Read ↗

Effects of<i>MAPT</i>rs17649553 on Structural Network Integrity and Verbal Memory in Parkinson’s DiseaseSemantic proximity Read ↗

Energetic implications of fMRI-based nodal complex network metrics: a complex picture unfolds across diverse brain statesSemantic proximity Read ↗

Functional Connectivity Analysis in Heterozygous Glucocerebrosidase Mutation Carriers.Semantic proximity Read ↗

Directed brain connectivity identifies widespread functional network changes in Parkinson’s diseaseSemantic proximity Read ↗

Adaptive and pathological connectivity responses in Parkinson’s disease brain networksSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.