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Article

Multimodal FMRI resting-state functional connectivity in granulin mutations: the case of fronto-parietal dementia.

PloS one - 1 Jan 2014

Premi Enrico, Cauda Franco, Gasparotti Roberto, Diano Matteo, Archetti Silvana, Padovani Alessandro, Borroni Barbara

Abstract excerpt

BACKGROUND: Monogenic dementias represent a great opportunity to trace disease progression from preclinical to symptomatic stages. Frontotemporal Dementia related to Granulin (GRN) mutations presents a specific framework of brain damage, involving fronto-temporal regions and long inter-hemispheric white matter bundles. Multimodal resting-state functional MRI (rs-fMRI) is a promising tool to carefully describe...

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Identifiers

PMID: 25188321
DOI: 10.1371/journal.pone.0106500
PMCID: PMC4154688

Genes

GRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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