Article
Nigral and striatal connectivity alterations in asymptomatic LRRK2 mutation carriers: A magnetic resonance imaging study.
Movement disorders : official journal of the Movement Disorder Society - 1 Dec 2016
Vilas Dolores, Segura Bàrbara, Baggio Hugo C, Pont-Sunyer Claustre, Compta Yaroslau, Valldeoriola Francesc, José Martí María, Quintana María, Bayés Angels, Hernández-Vara Jorge, Calopa Matilde, Aguilar Miquel, Junqué Carme, Tolosa Eduardo
Abstract excerpt
BACKGROUND: The study of functional connectivity by means of magnetic resonance imaging (MRI) in asymptomatic LRRK2 mutation carriers could contribute to the characterization of the prediagnostic phase of LRRK2-associated Parkinson's disease (PD). The objective of this study was to characterize MRI functional patterns during the resting state in asymptomatic LRRK2 mutation carriers. METHODS: We acquired...
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