Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants of aldehyde oxidase (AOX) 1 in cynomolgus and rhesus macaques.

Xenobiotica; the fate of foreign compounds in biological systems - 1 Apr 2021

Uno Yasuhiro, Uehara Shotaro, Murayama Norie, Yamazaki Hiroshi

Abstract excerpt

The cynomolgus macaque is a non-human primate species widely used in drug metabolism studies. Despite the importance of genetic polymorphisms in cytosolic aldehyde oxidase (AOX) 1 in humans, genetic variants have not been investigated in cynomolgus or rhesus macaques.Genetic variants in AOX1 were identified and allele frequencies were assessed using the genomes of 24 cynomolgus and 8 rhesus macaques. The analysis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype
Share to Macaca fascicularis
Share to Macaca mulatta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 33434089
DOI: 10.1080/00498254.2021.1874564

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants of aldehyde oxidase (AOX) 1 in cynomolgus and rhesus macaques.PMID 33434089Read ↗

The role of aldehyde oxidase in drug metabolism.Semantic proximity Read ↗

Structure and function of mammalian aldehyde oxidases.Semantic proximity Read ↗

The impact of single nucleotide polymorphisms on human aldehyde oxidase.Semantic proximity Read ↗

Evolution, expression, and substrate specificities of aldehyde oxidase enzymes in eukaryotesSemantic proximity Read ↗

Structural basis for the role of mammalian aldehyde oxidases in the metabolism of drugs and xenobiotics.Semantic proximity Read ↗

Genetic variants of CYP3A4 and CYP3A5 in cynomolgus and rhesus macaques.Semantic proximity Read ↗

Optimization of the Expression of Human Aldehyde Oxidase for Investigations of Single-Nucleotide Polymorphisms.Semantic proximity Read ↗

Systematic exploration of predicted destabilizing nonsynonymous single nucleotide polymorphisms (nsSNPs) of human aldehyde oxidase: A Bio-informatics study.Semantic proximity Read ↗

Development of genotyping method for functionally relevant variants of cytochromes P450 in cynomolgus macaques.Semantic proximity Read ↗

A single nucleotide polymorphism causes enhanced radical oxygen species production by human aldehyde oxidase.Semantic proximity Read ↗

Population distribution of human flavin-containing monooxygenase form 3: gene polymorphisms.Semantic proximity Read ↗

906 variations among 27 genes encoding cytochrome P450 (CYP) enzymes and aldehyde dehydrogenases (ALDHs) in the Japanese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.