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Article

Genetic variants of CYP3A4 and CYP3A5 in cynomolgus and rhesus macaques.

Drug metabolism and disposition: the biological fate of chemicals - 1 Feb 2010

Uno Yasuhiro, Matsushita Akinori, Osada Naoki, Uehara Shotaro, Kohara Sakae, Nagata Ryoichi, Fukuzaki Koichiro, Utoh Masahiro, Murayama Norie, Yamazaki Hiroshi

Abstract excerpt

Cynomolgus and rhesus macaques are frequently used in preclinical trials due to their close evolutionary relationships to humans. We conducted an initial screening for genetic variants in cynomolgus and rhesus macaque genes orthologous to human CYP3A4 and CYP3A5. Genetic screening of 78 Indochine...

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PMID: 19910514
DOI: 10.1124/dmd.109.029710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19910514-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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