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Article

Population distribution of human flavin-containing monooxygenase form 3: gene polymorphisms.

Drug metabolism and disposition: the biological fate of chemicals - 1 Dec 2001

Cashman J R, Zhang J, Leushner J, Braun A

Abstract excerpt

The N-oxygenation of amines by the human flavin-containing monooxygenase (form 3) (FMO3) represents an important means for the conversion of lipophilic nucleophilic heteroatom-containing compounds into more polar and readily excreted products. Certain mutations of the human FMO3 gene have been linked to abnormal drug or chemical metabolism. For example, abnormal N-oxygenation of trimethylamine has been shown to...

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Source

Identifiers

PMID: 11717182

Genes

FMO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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