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Article

Structure and function of mammalian aldehyde oxidases.

Archives of toxicology - 1 Apr 2016

Terao Mineko, Romão Maria João, Leimkühler Silke, Bolis Marco, Fratelli Maddalena, Coelho Catarina, Santos-Silva Teresa, Garattini Enrico

Abstract excerpt

Mammalian aldehyde oxidases (AOXs; EC1.2.3.1) are a group of conserved proteins belonging to the family of molybdo-flavoenzymes along with the structurally related xanthine dehydrogenase enzyme. AOXs are characterized by broad substrate specificity, oxidizing not only aromatic and aliphatic aldehydes into the corresponding carboxylic acids, but also hydroxylating a series of heteroaromatic rings. The number of...

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Identifiers

PMID: 26920149
DOI: 10.1007/s00204-016-1683-1

Genes

AOX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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