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Article

The role of aldehyde oxidase in drug metabolism.

Expert opinion on drug metabolism & toxicology - 1 Apr 2012

Garattini Enrico, Terao Mineko

Abstract excerpt

INTRODUCTION: Aldehyde oxidases (AOXs) are molybdo-flavoenzymes with complex evolutionary profiles, as the number and types of active AOX genes vary according to the animal species considered. Humans and higher primates have a single functional AOX1 gene, while rodents are endowed with four AOXs. Along with the endoplasmic cytochrome P450 system (CYP450), cytoplasmic AOX1 is the major enzyme involved in the...

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Identifiers

PMID: 22335465
DOI: 10.1517/17425255.2012.663352

Genes

AOX1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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