Article
Identification of novel SNPs associated with coronary artery disease and birth weight using a pleiotropic cFDR method.
Aging - 19 Dec 2020
Wu Xinrui, Lin Xu, Li Qi, Wang Zun, Zhang Na, Tian Mengyuan, Wang Xiaolei, Deng Hongwen, Tan Hongzhuan
Abstract excerpt
OBJECTIVES: Clinical and epidemiological findings indicate an association between coronary artery disease (CAD) and low birth weight (BW). However, the mechanisms underlying this relationship are largely unknown. Here, we aimed to identify novel single-nucleotide polymorphisms (SNPs) associated with CAD, BW, and their shared pleiotropic loci, and to detect the potential causal relationship between CAD and BW....
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