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Article

Multiomics Screening Identifies Molecular Biomarkers Causally Associated With the Risk of Coronary Artery Disease.

Circulation. Genomic and precision medicine - 1 Dec 2020

Nikpay Majid, Soubeyrand Sebastien, Tahmasbi Rasool, McPherson Ruth

Abstract excerpt

BACKGROUND: In this study, we aimed to investigate functional mechanisms underlying coronary artery disease (CAD) loci and find molecular biomarkers for CAD. METHODS: We devised a multiomics data analysis approach based on Mendelian randomization and utilized it to search for molecular biomarkers causally associated with the risk of CAD within genomic regions known to be associated with CAD. RESULTS: Through our...

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PMID: 32969717
DOI: 10.1161/CIRCGEN.119.002876

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