Article
Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors.
Circulation research - 8 Jan 2016
LeBlanc Marissa, Zuber Verena, Andreassen Bettina Kulle, Witoelar Aree, Zeng Lingyao, Bettella Francesco, Wang Yunpeng, McEvoy Linda K, Thompson Wesley K, Schork Andrew J, Reppe Sjur, Barrett-Connor Elizabeth, Ligthart Symen, Dehghan Abbas, Gautvik Kaare M, Nelson Christopher P, Schunkert Heribert, Samani Nilesh J, Ridker Paul M, Chasman Daniel I, Aukrust Pål, Djurovic Srdjan, Frigessi Arnoldo, Desikan Rahul S, Dale Anders M, Andreassen Ole A
Abstract excerpt
RATIONALE: Coronary artery disease (CAD) is a critical determinant of morbidity and mortality. Previous studies have identified several cardiovascular disease risk factors, which may partly arise from a shared genetic basis with CAD, and thus be useful for discovery of CAD genes. OBJECTIVE: We aimed to improve discovery of CAD genes and inform the pathogenic relationship between CAD and several cardiovascular...
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