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Article

Novel common variants associated with body mass index and coronary artery disease detected using a pleiotropic cFDR method.

Journal of molecular and cellular cardiology - 1 Nov 2017

Lv Wan-Qiang, Zhang Xue, Zhang Qiang, He Jing-Yang, Liu Hui-Min, Xia Xin, Fan Kun, Zhao Qi, Shi Xue-Zhong, Zhang Wei-Dong, Sun Chang-Qing, Deng Hong-Wen

Abstract excerpt

Genome-wide association studies (GWAS) have been successfully applied in identifying single nucleotide polymorphisms (SNPs) associated with body mass index (BMI) and coronary heart disease (CAD). However, the SNPs to date can only explain a small percentage of the genetic variances of traits. Here, we applied a genetic pleiotropic conditional false discovery rate (cFDR) method that combines summary statistic p...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28843344
DOI: 10.1016/j.yjmcc.2017.08.011
PMCID: PMC5812278

Genes

CAD
ATXN2
CNNM2
HIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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