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The causal relationships and potential pathways between birth weight and cardiovascular diseases: A human genomics study.

Medicine - 26 Jun 2026

Li Xinxi, Cao Yuheng, Cai Jiarui, Yu Chuan, Li Lin, Ge Qiaoyue, Liu Zhenmi, Xiao Chenghan

Abstract excerpt

The causal relationships and potential pathways between birth weight (BW) and various cardiovascular diseases (CVDs) remain unclear, particularly when discriminating maternal and fetal contributions of BW to CVDs. Leveraging the genome-wide association studies (GWASs) of BW (N = 321,223) and a range of CVDs (ncases = 43,676-181,522), we performed a 2-sample Mendelian randomization (MR) analysis to estimate the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42363482
DOI: 10.1097/MD.0000000000049315
PMCID: PMC13313791

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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