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Article

Identification of novel functional CpG-SNPs associated with type 2 diabetes and coronary artery disease.

Molecular genetics and genomics : MGG - 1 May 2020

Wang Zun, Qiu Chuan, Lin Xu, Zhao Lan-Juan, Liu Yong, Wu Xinrui, Wang Qian, Liu Wei, Li Kelvin, Deng Hong-Wen, Tang Si-Yuan, Shen Hui

Abstract excerpt

Genome-wide association studies (GWASs) have identified hundreds of single nucleotide polymorphisms (SNPs) associated with type 2 diabetes (T2D) and coronary artery disease (CAD), respectively. Nevertheless, these studies were generally performed for single-trait/disease and failed to assess the pleiotropic role of the identified variants. To identify novel functional loci and the pleiotropic relationship between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32162118
DOI: 10.1007/s00438-020-01651-3
PMCID: PMC7883506

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