Article
Amyotrophic lateral sclerosis phenotypes significantly differ in terms of magnetic susceptibility properties of the precentral cortex.
European radiology - 1 Jul 2021
Conte Giorgio, Contarino Valeria Elisa, Casale Silvia, Morelli Claudia, Sbaraini Sara, Scola Elisa, Trogu Francesca, Siggillino Silvia, Cinnante Claudia Maria, Caschera Luca, Lo Russo Francesco Maria, Triulzi Fabio Maria, Silani Vincenzo
Abstract excerpt
OBJECTIVES: The aim of our study was to investigate whether the magnetic susceptibility varies according to the amyotrophic lateral sclerosis (ALS) phenotypes based on the predominance of upper motor neuron (UMN)/lower motor neuron (LMN) impairment. METHODS: We retrospectively collected imaging and clinical data of 47 ALS patients (12 with UMN predominance (UMN-ALS), 16 with LMN predominance (LMN-ALS), and 19...
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