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Article

Imaging-derived neuromuscular ultrasound phenotypes are associated with functional status in amyotrophic lateral sclerosis.

Journal of neurology - 21 Feb 2026

Wang Ying, Zhang Hao, Yang Tianhua, Luo Jialei, Lin Ting, Yan Xinyi, Ding Junlin, Qiu Yuxuan, Zhao Min, Yang Gaoyi

Abstract excerpt

BACKGROUND: Amyotrophic lateral sclerosis (ALS) presents with marked clinical heterogeneity, complicating diagnosis and management. Neuromuscular ultrasound (NMUS) provides a non-invasive means to visualize peripheral nerve and muscle integrity, but its potential to delineate ALS subtypes has not been systematically explored. OBJECTIVE: To identify clinically meaningful ALS subgroups through unsupervised...

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Identifiers

PMID: 41723333
DOI: 10.1007/s00415-026-13705-4
PMCID: PMC12924791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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