Article
MR spectroscopy findings in early stages of motor neuron disease.
AJNR. American journal of neuroradiology - 1 Nov 2010
van der Graaff M M, Lavini C, Akkerman E M, Majoie Ch B, Nederveen A J, Zwinderman A H, Brugman F, van den Berg L H, de Jong J M B V, de Visser M
Abstract excerpt
BACKGROUND AND PURPOSE: Upper motor neuron degeneration varies in different phenotypes of MND. We used single-voxel MR spectroscopy of the primary motor cortex to detect corticomotoneuron degeneration and glial hyperactivity in different phenotypes of MND with a relatively short disease duration, contributing to further delineation of the phenotypes. MATERIALS AND METHODS: We prospectively included patients with...
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