Article
Clinical Profiles and Patterns of Neurodegeneration in Amyotrophic Lateral Sclerosis: A Cluster-Based Approach Based on MR Imaging Metrics.
AJNR. American journal of neuroradiology - 1 Apr 2023
Milella G, Introna A, Mezzapesa D M, D'Errico E, Fraddosio A, Ucci M, Zoccolella S, Simone I L
Abstract excerpt
BACKGROUND AND PURPOSE: The previous studies described phenotype-associated imaging findings in amyotrophic lateral sclerosis (ALS) with a prior categorization of patients based on clinical characteristics. We investigated the natural segregation of patients through a radiologic cluster-based approach without a priori patient categorization using 3 well-known prognostic MR imaging biomarkers in ALS, namely...
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