Article
Cortical thickness in ALS: towards a marker for upper motor neuron involvement.
Journal of neurology, neurosurgery, and psychiatry - 1 Mar 2015
Walhout Renée, Westeneng Henk-Jan, Verstraete Esther, Hendrikse Jeroen, Veldink Jan H, van den Heuvel Martijn P, van den Berg Leonard H
Abstract excerpt
OBJECTIVE: Examine whether cortical thinning is a disease-specific phenomenon across the spectrum of motor neuron diseases in relation to upper motor neuron (UMN) involvement. METHODS: 153 patients (112 amyotrophic lateral sclerosis (ALS), 19 patients with a clinical UMN phenotype, 22 with a lower motor neuron (LMN) phenotype), 60 healthy controls and 43 patients with an ALS mimic disorder were included for a...
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