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Article

Motor-evoked potentials in amyotrophic lateral sclerosis: potential implications in detecting subclinical UMN involvement in lower motor neuron phenotype.

Journal of neurology - 1 Dec 2020

Zoccolella Stefano, Mastronardi Antonella, Scarafino Antonio, Iliceto Giovanni, D'Errico Eustachio, Fraddosio Angela, Tempesta Irene, Morea Antonella, Scaglione Gaspare, Introna Alessandro, Simone Isabella Laura

Abstract excerpt

BACKGROUND: In amyotrophic lateral sclerosis (ALS), the involvement of lower motor neuron is well defined by electromyography, whereas a reliable marker of upper motor neuron (UMN) damage still lacks. Aim of the study was to estimate the role of transcranial magnetic stimulation (TMS)-induced motor-evoked potentials (MEPs) as marker of subclinical UMN involvement. METHODS: Clinical evidence of UMN damage was...

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Identifiers

PMID: 32676769
DOI: 10.1007/s00415-020-10073-5
PMCID: PMC7674351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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