Article
CRISPR/Cas9 Induced Somatic Recombination at the CRTISO Locus in Tomato.
Genes - 31 Dec 2020
Ben Shlush Ilan, Samach Aviva, Melamed-Bessudo Cathy, Ben-Tov Daniela, Dahan-Meir Tal, Filler-Hayut Shdema, Levy Avraham A
Abstract excerpt
Homologous recombination (HR) in somatic cells is not as well understood as meiotic recombination and is thought to be rare. In a previous study, we showed that Inter-Homologous Somatic Recombination (IHSR) can be achieved by targeted induction of DNA double-strand breaks (DSBs). Here, we designed a novel IHSR assay to investigate this phenomenon in greater depth. We utilized F1 hybrids from divergent parental...
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