Article

Redirecting DNA repair for efficient CRISPR-Cas-based gene targeting in tomato

2024-03-13

Abstract excerpt

<h4>ABSTRACT</h4> The CRISPR-Cas-based gene targeting (GT) method has enabled precise modifications of genomic DNA ranging from single base to several kilobase scales through homologous recombination (HR). In plant somatic cells, canonical nonhomologous end-joining (cNHEJ) is the predominant mechanism for repairing double-stranded breaks (DSBs), thus limiting the HR-mediated GT. In this study, we implemented vari...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 25e53030-ec0a-5763-9e32-0a2e018b5503
DOI: 10.1101/2024.03.12.584635

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Redirecting DNA repair for efficient CRISPR-Cas-based gene targeting in tomatoDOI 10.1101/2024.03.12.584635Read

Highly efficient homology-directed repair using transient CRISPR/Cpf1-geminiviral replicon in tomatoSemantic proximity Read

Comparison of Cas12a and Cas9-mediated mutagenesis in tomato cells.Semantic proximity Read

Research progress of genome editing and derivative technologies in plants.Semantic proximity Read

Development of Improved Fruit, Vegetable, and Ornamental Crops Using the CRISPR/Cas9 Genome Editing TechniqueSemantic proximity Read

Rapid breeding of parthenocarpic tomato plants using CRISPR/Cas9.Semantic proximity Read

A Robust CRISPR/Cas9 System for Convenient, High-Efficiency Multiplex Genome Editing in Monocot and Dicot Plants.Semantic proximity Read

CRISPR/Cas9-mediated efficient and heritable targeted mutagenesis in tomato plants in the first and later generations.Semantic proximity Read

CRISPR/Cas9 Induced Somatic Recombination at the CRTISO Locus in Tomato.Semantic proximity Read

CRISPR/Cas9-based precise excision of SlHyPRP1 domain(s) to obtain salt stress-tolerant tomato.Semantic proximity Read

Features affecting Cas9-Induced Editing Efficiency and Patterns in Tomato: Evidence from a Large CRISPR DatasetSemantic proximity Read

CRISPR/Cas9 editing of carotenoid genes in tomato.Semantic proximity Read

Targeted recombination between homologous chromosomes for precise breeding in tomato.Semantic proximity Read