Article

CRISPR/Cas9-induced breaks are insufficient to break linkage drag surrounding the ToMV locus of <i>Solanum lycopersicum</i>

2024-09-18

Abstract excerpt

Despite the success of CRISPR/Cas9 in inducing DNA double-strand breaks (DSBs) for genome editing, achieving targeted recombination in somatic cells remains challenging, particularly at recombination cold spots like the Tomato Mosaic Virus (ToMV) resistance locus in Solanum lycopersicum . We investigated the potential of CRISPR/Cas9-induced targeted recombination in somatic cells to overcome linkage drag surround...

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Literature Corpus work: a0dc1ae3-4224-5fb8-a411-a363997b03b1
DOI: 10.1101/2024.09.17.613470

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