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Article

Targeted recombination between homologous chromosomes for precise breeding in tomato.

Nature communications - 26 May 2017

Filler Hayut Shdema, Melamed Bessudo Cathy, Levy Avraham A

Abstract excerpt

Homologous recombination (HR) between parental chromosomes occurs stochastically. Here, we report on targeted recombination between homologous chromosomes upon somatic induction of DNA double-strand breaks (DSBs) via CRISPR-Cas9. We demonstrate this via a visual and molecular assay whereby DSB induction between two alleles carrying different mutations in the PHYTOENE SYNTHASE (PSY1) gene results in yellow fruits...

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PMID: 28548094
DOI: 10.1038/ncomms15605
PMCID: PMC5458649

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Source receipt: pubmed, retrieved 7 Sept 2026.

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