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Decoding Single-cell Landscape and Intercellular Crosstalk in the Transplanted Liver

22 Nov 2022

Abstract excerpt

BACKGROUND: Liver transplantation (LT) is the most effective treatment for various end-stage liver diseases. However, the cellular complexity and intercellular crosstalk of the transplanted liver have constrained analyses of graft reconstruction after LT. METHODS: We established an immune-tolerated orthotopic LT mouse model to understand the physiological process of graft recovery and intercellular crosstalk. We...

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PMID: 36413145
DOI: 10.1097/tp.0000000000004365

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