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Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversity

2021-12-02

Abstract excerpt

Blood samples are frequently collected in human studies of the immune system but poorly represent tissue-resident immunity. Understanding the immunopathogenesis of tissue-restricted diseases, such as chronic hepatitis B, necessitates direct investigation of local immune responses. We developed a workflow that enables frequent, minimally invasive collection of liver fine-needle aspirates in multi-site international...

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Literature Corpus work
1e1a3a50-2f52-5098-b9c1-d7ae4bd552e2
DOI
10.1101/2021.11.30.470634
Open publication

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Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversityDOI 10.1101/2021.11.30.470634
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