Article
Clinical implementation of single-cell RNA sequencing using liver fine needle aspirate tissue sampling and centralized processing captures compartment specific immuno-diversity
2021-12-02
Abstract excerpt
Blood samples are frequently collected in human studies of the immune system but poorly represent tissue-resident immunity. Understanding the immunopathogenesis of tissue-restricted diseases, such as chronic hepatitis B, necessitates direct investigation of local immune responses. We developed a workflow that enables frequent, minimally invasive collection of liver fine-needle aspirates in multi-site international...
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Identifiers and source
- Literature Corpus work
- 1e1a3a50-2f52-5098-b9c1-d7ae4bd552e2
- DOI
- 10.1101/2021.11.30.470634
