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Article

Genetic Liability to Depression and Risk of Coronary Artery Disease, Myocardial Infarction, and Other Cardiovascular Outcomes.

Journal of the American Heart Association - 5 Jan 2021

Lu Yunlong, Wang Zhen, Georgakis Marios K, Lin Hefeng, Zheng Liangrong

Abstract excerpt

Background Observational studies have indicated that depression is associated with coronary artery disease (CAD) and myocardial infarction. Nevertheless, causal associations between depression and cardiovascular diseases remain controversial. Hence, we conducted a Mendelian randomization and mediation analysis to evaluate the associations of depression-related genetic variants with CAD and myocardial infarction....

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Identifiers

PMID: 33372528
DOI: 10.1161/JAHA.120.017986
PMCID: PMC7955472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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