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Article

Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort.

Molecular psychiatry - 1 Jul 2020

Khandaker Golam M, Zuber Verena, Rees Jessica M B, Carvalho Livia, Mason Amy M, Foley Christopher N, Gkatzionis Apostolos, Jones Peter B, Burgess Stephen

Abstract excerpt

While comorbidity between coronary heart disease (CHD) and depression is evident, it is unclear whether the two diseases have shared underlying mechanisms. We performed a range of analyses in 367,703 unrelated middle-aged participants of European ancestry from UK Biobank, a population-based cohort study, to assess whether comorbidity is primarily due to genetic or environmental factors, and to test whether...

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PMID: 30886334
DOI: 10.1038/s41380-019-0395-3
PMCID: PMC7303009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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