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Article

Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors.

Journal of the American Heart Association - 20 Feb 2024

Shakt Gabrielle, Tsao Noah L, Levin Michael G, Walker Venexia, Kember Rachel L, Klarin Derek, Tsao Phil, Voight Benjamin F, Scali Salvatore T, Damrauer Scott M

Abstract excerpt

BACKGROUND: Major depressive disorder (MDD) has been identified as a causal risk factor for multiple forms of cardiovascular disease. Although observational evidence has linked MDD to peripheral artery disease (PAD), causal evidence of this relationship is lacking. METHODS AND RESULTS: Inverse variance weighted 2-sample Mendelian randomization was used to test the association the between genetic liability for MDD...

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Identifiers

PMID: 38362853
DOI: 10.1161/JAHA.123.030233
PMCID: PMC11010076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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