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Article

The relationship between major depression, attention-deficit hyperactivity disorder and coronary artery disease: A two-sample Mendelian randomization analysis.

Medicine - 17 Oct 2025

Zhang Xiaochen, Zhang Lei, Huo Suxia, Lu Yan, Hua Xiaokai, Zhong Xiaofei

Abstract excerpt

Coronary artery disease (CAD) constitutes a principal cause of global morbidity and mortality. Studies imply a connection between mental health disorders, especially major depression (MD) and attention-deficit hyperactivity disorder (ADHD), and the risk of CAD. To investigate the causal influence of genetic susceptibility to MD and attention-deficit/hyperactivity disorder (ADHD) on the risk of CAD, summary-level...

Read the complete abstract on PubMed

Topics

Humans
Attention Deficit Disorder with Hyperactivity
Mendelian Randomization Analysis
Major Depressive Disorder
Coronary Artery Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Genome-Wide Association Study

Genetic Predisposition to Disease

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 41189195
DOI: 10.1097/MD.0000000000043188
PMCID: PMC12537080

Genes

CAD

Provenance

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