Article
Genetic evidence of the causal relationships between psychiatric disorders and cardiovascular diseases.
Journal of psychosomatic research - 1 Feb 2025
Wen Yanchao, Wang Xingyu, Deng Liufei, Zhu Guiming, Si Xinyu, Gao Xue, Lu Xiangfeng, Wang Tong
Abstract excerpt
OBJECTIVE: Our primary objective is to investigate the causal relationships between 12 psychiatric disorders (PDs) and atrial fibrillation (AF), coronary artery disease (CAD), myocardial infarction (MI), and heart failure (HF). METHODS: Firstly, we used linkage disequilibrium score regression to calculate the genetic correlations between 12 PDs and 4 cardiovascular diseases (CVDs). Subsequently, we performed...
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