GenHITS: A network science approach to driver gene detection in human regulatory network using gene's influence evaluation.

Abstract excerpt

Cancer is among the diseases causing death, in which, cells uncontrollably grow and reproduce beyond the cell regulatory mechanism. In this disease, some genes are initiators of abnormalities and then transmit them to other genes through protein interactions. Accordingly, these genes are known as cancer driver genes (CDGs). In this regard, several methods have been previously developed for identifying cancer...

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