KatzDriver: A network based method to cancer causal genes discovery in gene regulatory network.

Abstract excerpt

One of the important problems in oncology is finding the genes that perturb the cell functionality and cause cancer. These genes, namely cancer driver genes (CDGs), when mutated, lead to the activation of the abnormal proteins. This abnormality is passed on to other genes by protein-protein interactions, which can cause cells to uncontrollably multiply and become cancerous. So, many methods have been introduced...

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