Article
DriverGroup: a novel method for identifying driver gene groups.
Bioinformatics (Oxford, England) - 30 Dec 2020
Pham Vu V H, Liu Lin, Bracken Cameron P, Goodall Gregory J, Li Jiuyong, Le Thuc D
Abstract excerpt
MOTIVATION: Identifying cancer driver genes is a key task in cancer informatics. Most existing methods are focused on individual cancer drivers which regulate biological processes leading to cancer. However, the effect of a single gene may not be sufficient to drive cancer progression. Here, we hypothesize that there are driver gene groups that work in concert to regulate cancer, and we develop a novel...
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