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Article

DMS-MaPseq for Genome-Wide or Targeted RNA Structure Probing In Vitro and In Vivo.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Tomezsko Phillip, Swaminathan Harish, Rouskin Silvi

Abstract excerpt

DMS-MaPseq is a chemical probing method combined with high throughput sequencing used to study RNA structure. Here we present a flexible protocol for adherent and suspension mammalian cells to analyze RNA structure in vitro or in vivo. The protocol provides instruction on either a targeted sequencing of a lncRNA of interest or a transcriptome-wide approach that provides structural data on all expressed RNAs,...

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PMID: 33326078
DOI: 10.1007/978-1-0716-1158-6_13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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