Article

RNA Infrastructure Profiling Illuminates Transcriptome Structure in Crowded Spaces

2023-10-09

Abstract excerpt

RNAs can fold into compact three-dimensional structures, and most RNAs undergo protein interactions in the cell. These compact and occluded environments can block the ability of structure-probing agents to provide useful data about the folding and modification of the underlying RNA. The development of probes that can analyze structure in crowded settings, and differentiate the proximity of interactions, can shed n...

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Literature Corpus work: dae6abec-9e1e-5b64-a9af-4108831e6633
DOI: 10.1101/2023.10.09.561413

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