Article
Influence of HLA-DQ2.5 Dose on Clinical Picture of Unrelated Celiac Disease Patients.
Nutrients - 9 Dec 2020
Airaksinen Laura, Laurikka Pilvi, Huhtala Heini, Kurppa Kalle, Salmi Teea, Saavalainen Päivi, Kaukinen Katri, Lindfors Katri
Abstract excerpt
The clinical phenotype of celiac disease varies considerably among patients and the dosage of HLA-DQ2.5 alleles has been suggested to be a contributing factor. We investigated whether HLA-DQ2.5 allele dosage is associated with distinct clinical parameters at the time of diagnosis and with patients' response to a gluten-free diet. The final cohort included 605 carefully phenotyped non-related Finnish celiac...
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