Article
Celiac disease and human leukocyte antigen genotype: accuracy of diagnosis in self-diagnosed individuals, dosage effect, and sibling risk.
Journal of pediatric gastroenterology and nutrition - 1 Jul 2000
Lewis C, Book L, Black J, Sawitzke A, Cannon-Albright L, Zone J, Neuhausen S
Abstract excerpt
BACKGROUND: Celiac disease is an autoimmune disorder of the small intestine characterized by intolerance to gluten. Traditionally, diagnosis is made by intestinal biopsy. Testing for immunoglobulin (Ig) A endomysial antibodies in the serum also is used for diagnosis. Biopsy and serology revert to normal with adherence to a gluten-free diet. Often, after an index case is diagnosed, siblings with symptoms adhere to...
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