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Article

NOX2-Derived Reactive Oxygen Species in Cancer.

Oxidative medicine and cellular longevity - 1 Jan 2020

Grauers Wiktorin Hanna, Aydin Ebru, Hellstrand Kristoffer, Martner Anna

Abstract excerpt

The formation of reactive oxygen species (ROS) by the myeloid cell NADPH oxidase NOX2 is critical for the destruction of engulfed microorganisms. However, recent studies imply that ROS, formed by NOX2+ myeloid cells in the malignant microenvironment, exert multiple actions of relevance to the growth and spread of neoplastic cells. By generating ROS, tumor-infiltrating myeloid cells and NOX2+ leukemic myeloid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33312338
DOI: 10.1155/2020/7095902
PMCID: PMC7721506

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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