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Article

Context-specific effects of NOX4 inactivation in acute myeloid leukemia (AML).

Journal of cancer research and clinical oncology - 1 Aug 2022

Demircan Muhammed Burak, Schnoeder Tina M, Mgbecheta Peter C, Schröder Katrin, Böhmer Frank-D, Heidel Florian H

Abstract excerpt

PURPOSE: Oxidative stress has been linked to initiation and progression of cancer and recent studies have indicated a potential translational role regarding modulation of ROS in various cancers, including acute myeloid leukemia (AML). Detailed understanding of the complex machinery regulating ROS including its producer elements in cancer is required to define potential translational therapeutic use. Based on...

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Identifiers

PMID: 35348887
DOI: 10.1007/s00432-022-03986-3
PMCID: PMC9293823

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