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Enhanced expression of NADPH oxidase Nox4 in human gliomas and its roles in cell proliferation and survival

28 May 2008

Abstract excerpt

Reactive oxygen species (ROS) have been attracting attention as mediators of various cell-signaling pathways. Nox-family NADPH oxidases have proven to be a major source of ROS production in various cell types and have crucial roles in various physiological and pathological processes. In this study, we show that Nox4, a member of Nox family, is prominently expressed in various neuroepithelial tumors by reverse...

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Share to Neuroinflammation and Neurodegeneration Mechanisms
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PMID: 18508317
DOI: 10.1002/ijc.23569

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