Growth Hormone Receptor Regulation in Cancer and Chronic Diseases

doi:10.3389/fendo.2020.597573

Article

Growth Hormone Receptor Regulation in Cancer and Chronic Diseases

18 Nov 2020

Abstract excerpt

both the JAK/STAT and the SRC pathways. Dysregulation of GHR signaling is associated with various diseases and chronic conditions such as acromegaly, cancer, aging, metabolic disease, fibroses, inflammation and autoimmunity. Numerous studies entailing the GHR signaling pathway have been conducted for various cancers. Diverse factors mediate the up- or down-regulation of GHR signaling through post-translational...

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