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The role of WD40 repeat-containing proteins in endocrine (dys)function

31 May 2023

Abstract excerpt

WD40 repeat-containing proteins play a key role in many cellular functions including signal transduction, protein degradation, and apoptosis. The WD40 domain is highly conserved, and its typical structure is a β-propeller consisting of 4-8 blades which probably serves as a scaffold for protein-protein interaction. Some WD40 repeat-containing proteins form part of the corepressor complex of nuclear hormone...

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PMID: 37256579
DOI: 10.1530/jme-22-0217

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