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Article

The ubiquitin-proteasome pathway regulates the availability of the GH receptor.

Endocrinology - 1 Apr 2002

van Kerkhof Peter, Smeets Mirjam, Strous Ger J

Abstract excerpt

GH promotes not only longitudinal growth in children but is active throughout life in protein, fat, and carbohydrate metabolism. The multiple actions of GH start when GH binds to the cell surface-expressed GH receptor. Effectiveness of the hormone depends both on its presence in the circulation and the availability of receptors at the cell surface of target cells. In this study, we examined the role of the...

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Identifiers

PMID: 11897680
DOI: 10.1210/endo.143.4.8755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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