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Ubiquitination of nuclear receptors

1 May 2017

Abstract excerpt

Nuclear receptors (NRs) are cellular proteins, which upon ligand activation, act to exert regulatory control over transcription and subsequent expression. Organized via systemic classification into seven subfamilies, NRs partake in modulating a vast expanse of physiological functions essential for maintenance of life. NRs display particular characteristics towards ubiquitination, the process of addition of...

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PMID: 28473472
DOI: 10.1042/cs20160708

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